The Simpsons season 3 episode 15
Episode title: Homer Alone
A stressed Marge vacations alone, leaving Bart and Lisa with Patty and Selma, and Maggie with Homer--until she leaves in search of Marge.
A stressed Marge vacations alone, leaving Bart and Lisa with Patty and Selma, and Maggie with Homer--until she leaves in search of Marge.